Principal Investigator: Reza Malekzadeh

-Professor of Internal Medicine -Tehran University of Medical Sciences
-Director, Digestive Disease Research Center

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 Approval date: 91/6/1

 Starting date: 91/8/23

 Goals: To investigate the prevalence of Non-communicable chronic disease in Fars province and predictors of these NCDs to design interventional studies to reduce burden of NCDs in this region and to use this result in a national scale. (MI/CVA/Cancer/CLD/CKD/.. )

 Study population: All resident (male and female)>=40 <=75 In Valashahr and 93 related villages

 Sampling method and sample size: All resident (male and female)>=40 <=75 were recruited in this study which included 10,431 samples.

 Data Collection: General questionnaire/FFQ/Limited Physical Examination (Bp/APM/Oral Health) Lab tests including: CBC, PLT, ALT, AST, Alkph, Bun, Cr, Chol, TG, LDL,HDL, FBS in all sujects. Fibroscan and Ultrasound in some subjects

Follow up Methods: All subjects follow up by telephone call every year and Repeated exposure measurement ever 5 tears . In case of event, patients file will be investigated and all documents will be recorded .

 Main Exposures: Chronic disease (MI/CVA/Cancer/CLD/CKD/.. )

 Outcomes: Assessment of main risk factors All events for all subjects Mortality

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